Composition for gene delivery comprising chitosan and liquid crystal formation material
US11318215B2 · kind B2 · utility
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3References
12Claims
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Assignee
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Key dates
| Filing date | Feb 28, 2014 |
| Grant date | May 3, 2022 |
| Priority date | — |
| Expiry date | Feb 28, 2034 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2320/32
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Disclosed herein is a composition for gene delivery which forms into liquid crystals in an aqueous fluid including chitosan and a liquid crystal formation material. The composition of the present invention including chitosan and a liquid crystal formation material improves the relatively low binding strength between chitosan and a gene, and also considerably increases the stability of a chitosan nanocomposite in blood serum, thereby performing highly efficient gene delivery and providing excellent stability, thus being useful as a gene therapeutic agent.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.