Patent · US Active

Pulmonary hypertension treatment

US11318331B2 · kind B2 · utility

8Cited by
105References
14Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMar 20, 2018
Grant dateMay 3, 2022
Priority date
Expiry dateJun 8, 2038

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61N2007/0078
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Disclosed herein is a therapeutically active agent usable in the treatment of pulmonary arterial hypertension (PAH), for use in the treatment of pulmonary arterial hypertension, as well as methods of treating PAH, said treatment and methods comprising administering such an active agent and effecting pulmonary artery denervation in the subject. In some aspects, a sub-therapeutically effective amount of the active agent is administered. In some aspects, the method is devoid of administering such an active agent for at least one month subsequent to the denervation. Further disclosed is a method of treating PAH comprising determining a responsiveness of the subject to at least one therapeutically active agent usable in treating PAH; and effecting pulmonary artery denervation in a subject responsive to the active agent(s).

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.