Patent · US Active

Methods of treating tumors with pro drugs

US11318332B2 · kind B2 · utility

8Cited by
65References
13Claims
0Family size

Assignee

Inventors

Key dates

Filing dateAug 11, 2021
Grant dateMay 3, 2022
Priority date
Expiry dateAug 11, 2041

Classification

  • Technology area (CPC B)Performing Operations; Transporting
  • CPC primaryB06B2201/76
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Methods of treating tumors by administering compounds to a patient are provided. Compounds such as pro drugs, e.g., 5-aminolevulinic acid (5-ALA), may be administered to the patient orally, by injection, intravenously, or topically, which then accumulate preferentially as compounds such as protoporphyrin IX (PpIX) in tumor cells. After such accumulation, compounds such as PpIX are then activated in various aspects to treat tumors cells, thereby treating cancer. Cancers such as glioblastoma may be treated.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.