Alpha alkylation of aldehyde with a polycyclic olefin
US11319272B2 · kind B2 · utility
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16Claims
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Key dates
| Filing date | Apr 17, 2018 |
| Grant date | May 3, 2022 |
| Priority date | — |
| Expiry date | Dec 29, 2038 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C2602/42
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The alpha alkylation of an aldehyde with a polycyclic olefin followed by a ring opening step is presented in order to provide a compound of formula (I) in the form of any one of its stereoisomers or a mixture thereof and where in R represents a hydrogen atom or C1-8 linear alkyl group; R1, R2, R3, and R4 represent, when taken separately, independently of each other, a hydrogen atom or a C1-2 linear alkyl group or a C3-4 linear or branched alkyl group; or R2 and R3, when taken together, represent a C4-10 linear, branched or cyclic alkanediyl group and n is 1 or 2 is presented.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.