Compound used as autophagy regulator, and preparation method therefor and uses thereof

US11319303B2 · kind B2 · utility

Assignee

• WIGEN BOIMEDICINE TECHNOLOGY (SHANGHAI) CO., LTD. · CN

Inventors

• Cheng LUO · Shanghai, CN
• Yuli Xie · Shanghai, CN
• Bing Zhou · Ann Arbor, US
• Zhiyi Yao · Shanghai, CN
• Liyan Yue · Shanghai, CN
• Wei Wan · Shanghai, CN
• Bidong Zhang · Shanghai, CN
• Yuanyuan Zhang · Beijing, CN
• Hualiang Jiang · Shanghai, CN
• Kaixian Chen · Shanghai, CN

Key dates

• Filing date: May 18, 2018
• Grant date: May 3, 2022
• Expiry date: May 18, 2038

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C2601/14
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

It is related to compounds used as autophagy modulators and a method for preparing and using the same, specifically providing a compound of general formula (I), or pharmaceutically acceptable salts thereof, which is a type of autophagy modulators, particularly mammalian ATG8 homologues modulators.