Tricyclic furan-substituted piperidinedione compound

US11319330B2 · kind B2 · utility

Assignee

• Medshine Discovery Inc. · CN

Inventors

• Maoyi LEI · Shanghai, CN
• Yunfu Luo · Shanghai, CN
• Yu Xu · Shanghai, CN
• Guoli Zhang · Tianjin, CN
• Jinghong Dong · Shanghai, CN
• Jian Li · Shanghai, CN
• Shuhui CHEN · Shanghai, CN

Key dates

• Filing date: Sep 9, 2019
• Grant date: May 3, 2022
• Expiry date: Sep 9, 2039

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D498/04
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Disclosed are a series of tricyclic furan-substituted piperidinedione compounds and an application thereof in preparing a drug for treating a disease related to CRBN protein. In particular, disclosed is a derivative compound represented by formula (I) or a pharmaceutically acceptable salt thereof.