Method for producing self-assembling paramyxoviral nucleocapsid-like particles and their uses

US11319350B2 · kind B2 · utility

Assignees

• CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE · FR
• UNIVERSITE GRENOBLE ALPES · FR
• COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES · FR

Inventors

• Martin Blackledge · Grenoble, FR
• Marlène Ringkjobing-Jensen · Grenoble, FR
• Sigrid Milles · Grenoble, FR
• Robertus Ruigrok · Grenoble, FR
• Guy Schoehn · Grenoble, FR
• Guillaume Communie · Grenoble, FR

Key dates

• Filing date: Jun 6, 2017
• Grant date: May 3, 2022
• Expiry date: Jun 6, 2037

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12N2760/18451
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

Embodiments of the disclosure relate to the domain of virology of Paramyxoviruses. The disclosure concerns a method for producing self-assembling paramyxoviral particles and a method for identifying a compound able to inhibit the replication or the transcription of a Paramyxovirus. The disclosure also pertains to the nucleocapsid-like particles obtainable by the method of the invention and their use for biotechnological and pharmaceutical applications.