Acoustic blood separation processes and devices
US11324873B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Sep 6, 2016 |
| Grant date | May 10, 2022 |
| Priority date | — |
| Expiry date | Mar 18, 2037 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB01D2221/10
- WIPO fieldChemical engineering
- WIPO sectorChemistry
Abstract
Acoustophoretic devices are disclosed. The devices include a flow chamber, an ultrasonic transducer, a reflector, an inlet, a filtrate outlet, a concentrate outlet, and optionally a lipid collection trap. The ultrasonic transducer and reflector create a multi-dimensional acoustic standing wave in the flow chamber that traps and separates red blood cells and/or lipids from blood. Concentrated red blood cells can be recovered via the concentrate outlet, the lipids can be recovered via the lipid collection trap, and the remaining blood can be recovered via the filtrate outlet. Methods for separating blood components (e.g., red blood cells, lipids, platelets, white blood cells) from blood are also disclosed. The red blood cells can undergo washing with a solvent to remove undesired admixtures. Cryoprotectants can be added or removed from the blood.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.