Systems and methods for indicating lifetime of an NO2-to-NO reactor cartridge used to deliver NO for inhalation therapy to a patient

US11324912B2 · kind B2 · utility

Assignee

• Mallinckrodt Pharmaceuticals Ireland Limited · IE

Inventors

• Jaron M. Acker · Madison, US
• Muhammad Asif · New Fairfield, US
• Craig Flanagan · Belmar, US
• Douglas Alan Greene · Jalan Pedongkelan, US
• Sarah Jayne Ridley · Wantage, US
• Frank K. Schweighardt · Emmaus, US
• Lien-Lung Sheu · Scotch Plains, US

Key dates

• Filing date: Nov 26, 2019
• Grant date: May 10, 2022
• Expiry date: Oct 29, 2040

Classification

• Technology area (CPC B): Performing Operations; Transporting
• CPC primary: B01D2259/4533
• WIPO field: Chemical engineering
• WIPO sector: Chemistry

Abstract

The principles and embodiments of the present invention relate to methods and systems for safely providing NO to a recipient for inhalation therapy. There are many potential safety issues that may arise from using a reactor cartridge that converts NO2 to NO, including exhaustion of consumable reactants of the cartridge reactor. Accordingly, various embodiments of the present invention provide systems and methods of determining the remaining useful life of a NO2-to-NO reactor cartridge and/or a break-through of NO2, and providing an indication of the remaining useful life and/or break-through.