Patent · US Active

Method of fermentative alpha-ionone production

US11326173B2 · kind B2 · utility

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4References
4Claims
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Key dates

Filing dateAug 28, 2015
Grant dateMay 10, 2022
Priority date
Expiry dateNov 28, 2035

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12Y505/01018
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

The present invention concerns a method of producing and enantiomerically pure alpha-ionone. Further, the invention concerns a nucleic acid that comprises a sequence that encodes a lycopene-epsilon-cyclase (EC), a lycopene-epsilon-cyclase (EC), plasmids, which encode components of the alpha-ionone biosynthesis and a microorganism that contains heterologous nucleotide sequences which encode the enzymes geranylgeranyl-diphosphate-synthase, isopentenyl-diphosphate-isomerase (IPI), phytoene desaturase-dehydrogenase (crtI), phytoene synthase (crtB), lycopene-epsilon-cyclase (EC) and carotenoid-cleavage-dioxygenase (CCD1). Further, the invention concerns a method of producing highly pure epsilon-carotene.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.