Affinity mediated transport amplification
US11326199B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Jun 4, 2021 |
| Grant date | May 10, 2022 |
| Priority date | — |
| Expiry date | Jun 4, 2041 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB01L2400/043
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A method for amplification in a microfluidic assay, includes binding an analyte to a transport element, wherein the transport element includes a particle and a first antibody element and the analyte is bound to the first antibody element; moving the transport element with the analyte towards a tracer storage site including tracer elements which includes a first binder element, a label element and a second antibody element; binding the analyte to the second antibody element; moving the transport element with the analyte and the tracer element towards a tracer transport site including second binder elements; binding the first binder element with a second binder element; moving the transport element with the analyte towards the tracer storage site so that the analyte is detached from the second antibody element of the tracer element while the first binder element remains bound to the second binder element.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.