Reusable initiators for synthesizing nucleic acids
US11331643B2 · kind B2 · utility
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19References
7Claims
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Key dates
| Filing date | Jan 29, 2019 |
| Grant date | May 17, 2022 |
| Priority date | — |
| Expiry date | Mar 22, 2040 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Y207/07031
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The invention provides improved methods for synthesizing polynucleotides, such as DNA and RNA, using renewable initiators coupled to a solid support. Using the methods of the invention, specific sequences of polynucleotides can be synthesized de novo, base by base, in an aqueous environment, without the use of a nucleic acid template.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.