Patent · US Active

Analytical process for predicting the therapeutic effect of BH3 mimetics

US11333660B2 · kind B2 · utility

0Cited by

0References

16Claims

0Family size

Assignee

MEDIZINISCHE HOCHSCHULE HANNOVER · DE

Inventors

Michaela Scherr · Hemmingen, DE
Matthias Eder · Freiburg (Elbe), DE

Key dates

Filing date	Apr 3, 2018
Grant date	May 17, 2022
Priority date	—
Expiry date	Oct 25, 2038

Classification

Technology area (CPC G)Physics
CPC primaryG01N2800/52
WIPO fieldMeasurement
WIPO sectorInstruments

Abstract

The present invention relates to an analytical in vitro process for predicting the therapeutic effectiveness of at least one pharmaceutical compound in the treatment of leukemia and/or lymphoma, the process analysing the transmembrane potential of mitochondria in cells isolated from a patient by quantification of fluorescence emitted from a dye indicating induction of apoptosis.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.