Methods for tissue passivation
US11337792B2 · kind B2 · utility
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1References
7Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 18, 2019 |
| Grant date | May 24, 2022 |
| Priority date | — |
| Expiry date | Jan 10, 2040 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61N5/0624
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
One aspect of the invention provides a method of preventing or reducing stenosis in a subject. The method includes implanting a passivated graft comprising vein into an artery. The implanting of the graft replaces and/or bypasses a diseased segment of the artery. The passivated graft including vein is prepared by exposing the exterior surface of the passivated graft comprising vein to a tissue structure stabilizing agent (“TSSA”) under conditions sufficient to promote cross-linking of proteins within the vein.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.