Compositions and methods for viral sensitization

US11339146B2 · kind B2 · utility

Assignee

• Ottawa Hospital Research Institute and University of Ottawa · CA

Inventors

• Jean-Simon Diallo · Ottawa, CA
• Christopher N. Boddy · Ottawa, CA
• Mark Dornan · Point Pleasant, US
• Ramya Krishnan · Ottawa, CA
• Rozanne Arulanandam · Mississauga, CA
• Fabrice Le Boeuf · Gatineau, CA
• Jeffrey Smith · Attica, US
• Andrew Macklin · Ottawa, CA

Key dates

• Filing date: May 18, 2020
• Grant date: May 24, 2022
• Expiry date: May 18, 2040

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y02A50/30
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Provided are compounds of Formula (II) that enhance the efficacy of viruses by increasing spread of the virus in cells, increasing the titer of virus in cells, or increasing the antigen expression from a virus, gene or trans-gene expression from a virus, or virus protein expression in cells. Other uses, compositions and methods of using same are also provided.