Patent · US Active

Phosphate and phosphonate derivatives of 7-amino-5-thio-thiazolo[4,5-d]pyrimidines and their use in treating conditions associated with elevated levels of CX3CR1 and/or CX3CL1

US11339183B2 · kind B2 · utility

1Cited by

0References

17Claims

0Family size

Assignee

Kancera AB · SE

Inventors

Jan Vågberg · Sollentuna, SE
Styrbjörn Byström · Solna, SE
Elisabeth Olsson · Sollentuna, SE
Mattias Jonsson · Uppsala, SE

Key dates

Filing date	Jul 9, 2021
Grant date	May 24, 2022
Priority date	—
Expiry date	Jul 9, 2041

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61P35/00
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

There is provided a compound of formula I, wherein R1, R2, Q1 and are as defined herein, which compounds are useful in the treatment of diseases and disorders associated with elevated levels of CX3CR1 and/or CX3CL1, in particular acute and/or chronic inflammation, eye diseases, lung diseases, skin diseases, joint and/or bone diseases, autoimmune diseases, cardiovascular diseases, metabolic diseases, brain diseases, neurodegenerative diseases, pain, cancer, liver diseases, kidney diseases, gastrointestinal diseases, human immunodeficiency virus and mood disorders.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.