Method for assessing the risk of complications in patients with systemic inflammatory response syndrome (sirs)
US11339438B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Dec 1, 2016 |
| Grant date | May 24, 2022 |
| Priority date | — |
| Expiry date | Feb 21, 2037 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q2600/158
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The invention concerns a method of in vitro or ex vivo evaluation of the risk of complications in a patient who has sustained an insult or an infection generating a systemic inflammatory response syndrome, the method being characterized in that it comprises the step of detecting, in a biological sample obtained from said patient, at least one transcript of the IL7R gene, as well as measuring, in vitro or ex vivo, the quantity of at least one transcript of the IL7R gene, in a biological sample from a patient who has sustained an insult or an infection generating a systemic inflammatory response syndrome, in order to evaluate the risk of complications, and in particular of mortality, in said patient.The invention also concerns kits for measuring, in vitro or ex vivo, the quantity of at least one transcript of the IL7R gene in a biological sample.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.