Use of molecular marker Dkk-3 associated with muscle atrophy
US11340221B2 · kind B2 · utility
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Key dates
| Filing date | Apr 28, 2016 |
| Grant date | May 24, 2022 |
| Priority date | — |
| Expiry date | Sep 16, 2037 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q2600/158
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Disclosed are a protein molecular marker Dkk-3 protein associated with age-related muscle atrophy and the use thereof in the diagnosis of age-related muscle atrophy. The expression level of the Dkk-3 protein in amyotrophic cells is significantly higher than that in normal myocytes or tissues, and thus the Dkk-3 protein can be used as an effective marker for the detection of age-related muscle atrophy.
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