Squalene epoxidase in the diagnosis and treatment of non-alcoholic fatty liver diseases
US11340226B2 · kind B2 · utility
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6Claims
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Key dates
| Filing date | Mar 2, 2018 |
| Grant date | May 24, 2022 |
| Priority date | — |
| Expiry date | Jun 15, 2038 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2800/56
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention provides a method for providing a diagnosis or prognosis of a non-alcoholic fatty liver disease (NAFLD) in a subject by detecting expression level of the Squalene Epoxidase (SQLE) gene. A kit and device useful for such methods are also provided. In addition, the present invention provides a method for treating NAFLD by suppressing SQLE gene expression or activity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.