Micro-plate reader for ELISA testing

US11347000B2 · kind B2 · utility

Assignee

• The Regents of the University of California · US

Inventors

• Aydogan Ozcan · Los Angeles, US
• Brandon Berg · Calabasas, US
• Bingen Cortazar · Los Angeles, US
• Derek Tseng · Buena Park, US
• Steve Wei Feng · Los Angeles, US
• Haydar Ozkan · Los Angeles, US
• Omai Garner · Culver City, US
• Dino Di Carlo · Los Angeles, US

Key dates

• Filing date: Jun 17, 2016
• Grant date: May 31, 2022
• Expiry date: Oct 15, 2038

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N2201/08
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

A micro-plate reader for use with a portable electronic device having a camera includes an opto-mechanical attachment configured to attach/detach to the portable electronic device and includes an array of illumination sources. A slot in the opto-mechanical attachment is dimensioned to receive an optically transparent plate containing an array of wells. Optical fibers are located in the opto-mechanical attachment and transmit light from each well to a reduced size header having, wherein the fiber array in the header has a cross-sectional area that is ≤10× the cross-sectional area of the wells in the plate. A lens located in the opto-mechanical attachment transmits light from the header fibers to the camera. Software executed on the portable electronic device or other computer is used to process the images to generate qualitative clinical determinations and/or quantitative index values for the separate wells.