Methods for in vitro memory B cell differentiation and transduction with VSV-G pseudotyped viral vectors
US11352603B2 · kind B2 · utility
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18Claims
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Key dates
| Filing date | Feb 4, 2019 |
| Grant date | Jun 7, 2022 |
| Priority date | — |
| Expiry date | Feb 4, 2039 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2510/02
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present disclosure relates to the in vitro differentiation of memory B cells to plasmablasts or plasma cells and genetic modification of these cells to express a protein of interest, such as a specific antibody or other protein therapeutic.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.