Genomic engineering of pluripotent cells
US11352607B2 · kind B2 · utility
2Cited by
41References
28Claims
0Family size
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Key dates
| Filing date | Oct 17, 2019 |
| Grant date | Jun 7, 2022 |
| Priority date | — |
| Expiry date | Oct 17, 2039 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02A50/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Provided are methods and compositions for obtaining genome-engineered iPSCs, and derivative cells with stable and functional genome editing at selected sites. Also provided are cell populations or clonal cell lines derived from genome-engineered iPSCs, which comprise targeted integration of one or more exogenous polynucleotides, and/or in/dels in one or more selected endogenous genes.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.