Methods and compositions for treating malignant tumors associated with KRAS mutation
US11352628B2 · kind B2 · utility
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20Claims
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Key dates
| Filing date | Aug 14, 2019 |
| Grant date | Jun 7, 2022 |
| Priority date | — |
| Expiry date | Aug 14, 2039 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2320/32
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
This invention provides methods and compositions for preventing, treating or ameliorating one or more symptoms of a malignant tumor, which may be associated with KRAS mutation in a mammal in need thereof, by administering to the mammal a therapeutically effective amount of a composition comprising one or more RNAi molecules that are active in reducing expression of GST-π.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.