Use of lipid particles in medical diagnostics

US11353467B2 · kind B2 · utility

Assignee

• The Regents of the University of California · US

Inventors

• Katherine B. Louie · Walnut Creek, US
• Benjamin P. Bowen · Tempe, US
• Trent R. Northen · Walnut Creek, US

Key dates

• Filing date: Jan 23, 2014
• Grant date: Jun 7, 2022
• Expiry date: Jun 9, 2036

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N2800/7028
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

Disclosed herein are methods for identifying one or more diseased cells in a subject. Some embodiments include providing a biological sample derived from a subject, analyzing the biological sample by mass spectrometry, and determining the abundance of one or more lipids in the biological sample, wherein an altered abundance of the one or more lipids in the biological sample, as compared to a reference level, indicates a presence of one or more diseased cells in the subject from which the biological sample is derived.