Ultrasound frequency and microbubble size optimization in microbubble-enhanced ultrasound treatment
US11358007B2 · kind B2 · utility
2Cited by
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23Claims
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Key dates
| Filing date | Jun 29, 2018 |
| Grant date | Jun 14, 2022 |
| Priority date | — |
| Expiry date | Aug 23, 2039 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61N2007/027
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
Various approaches for enhancing treatment of target tissue using a source of focused ultrasound while limiting damage to non-target tissue include selecting a frequency of ultrasound waves transmitted from the source of focused ultrasound for generating a focus in the target tissue; providing microbubbles having the first size distribution such that at least 50% of the microbubbles have a radius smaller than a critical radius corresponding to a resonance frequency matching the selected frequency of ultrasound waves; and applying the ultrasound waves at the selected frequency to treat the target tissue.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.