Methods for the iodination of biomolecules
US11358982B2 · kind B2 · utility
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Key dates
| Filing date | Nov 1, 2017 |
| Grant date | Jun 14, 2022 |
| Priority date | — |
| Expiry date | Dec 15, 2037 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07B2200/05
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Provided herein are methods for iodinating biomolecules, including proteins and peptides. The methods can be used to successfully and efficiently iodinate biomolecules under relatively mild reaction conditions. As a consequence, the methods described herein can be used to iodinate biomolecules that include, for example, an oxidatively unstable moiety (e.g., an optical dye) without adversely impacting the oxidatively unstable moiety.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.