Anti-siglec-5 antibodies and methods of use thereof

US11359014B2 · kind B2 · utility

Assignee

• Alector LLC

Inventors

• Kate Monroe · Berkeley, US
• Helen LAM · Union City, US
• Patricia Culp · Oakland, US
• Arnon Rosenthal · Woodside, US

Key dates

• Filing date: May 15, 2018
• Grant date: Jun 14, 2022
• Expiry date: Jun 9, 2038

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K2317/92
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present disclosure is generally directed to compositions that include antibodies, e.g., monoclonal, chimeric, humanized antibodies, antibody fragments, etc., that specifically bind on or more epitopes within a Siglec-5 protein, e.g., human Siglec-5 or a mammalian Siglec-5, and use of such compositions in preventing, reducing risk, or treating an individual in need thereof.