Linked paired strand sequencing

US11359238B2 · kind B2 · utility

Assignee

• Singular Genomics Systems, Inc. · US

Inventors

• Eli N. Glezer · Del Mar, US
• Martin Maria Fabani · Encinitas, US
• Sabrina Shore · San Diego, US
• Daan Witters · Geetbets, BE

Key dates

• Filing date: Mar 5, 2021
• Grant date: Jun 14, 2022
• Expiry date: Mar 5, 2041

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12Q1/6855
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

Provided herein are methods for sequencing both strands of a double stranded nucleic acid fragment that improves fidelity and accuracy of a sequence determination compared to traditional next generation sequencing methods. Compositions and kits for use in the methods are also provided.