Patent · US Active

Microbial-based biosensors

US11360104B2 · kind B2 · utility

0Cited by

1References

29Claims

0Family size

Assignees

Inventors

James Galagan · Needham, US
Allison Dennis · Waltham, US
Catherine M. Klapperich · San Francisco, US
Mark W. Grinstaff · Brookline, US
Thuy N. Nguyen · Watertown, US
R. Baer · Boston, US
Uros Kuzmanovic · Brookline, US
Marjon Zamani · Brookline, US
Mingfu Chen · Boston, US
Margaret Chern · Brookline, US
Chloe Grazon · Boston, US

Key dates

Filing date	Dec 4, 2018
Grant date	Jun 14, 2022
Priority date	—
Expiry date	Feb 16, 2039

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K2319/60
WIPO fieldMeasurement
WIPO sectorInstruments

Abstract

Described herein are methods, compositions and processes related to a microbial-based biosensor system for the detection of small molecules and analytes based on an analyte-responsive transcription factor-DNA binding mechanism with either a ratiometric fluorescent output through Förster resonance energy transfer (FRET) or a redox sensor output for the quantification of the target analyte with high sensitivity.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.