Patent · US Active

Vaccine compositions having improved stability and immunogenicity

US11364294B2 · kind B2 · utility

1Cited by

20References

24Claims

0Family size

Assignee

Novavax, Inc. · US

Inventors

Gale Smith · Germantown, US
Ye Liu · Foster City, US
Jing-Hui Tian · Germantown, US
Michael J. MASSARE · Mount Airy, US
Sarathi BODDAPATI · Germantown, US
Erica Shane · McLean, US
Cynthia N. Oliver · Potomac, US
Gregory M. Glenn · Bethesda, US

Key dates

Filing date	Nov 21, 2017
Grant date	Jun 21, 2022
Priority date	—
Expiry date	Nov 21, 2037

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12N2760/18534
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Disclosed herein are nanoparticles suitable for use in vaccines. The nanoparticles present antigens from pathogens surrounded to and associated with a detergent core resulting in enhanced stability and good immunogenicity. Dosages, formulations, and methods for preparing the vaccines and nanoparticles are also disclosed.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.