Non-addictive analgesic sustained-release drug delivery system and preparation method thereof
US11364299B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Apr 10, 2013 |
| Grant date | Jun 21, 2022 |
| Priority date | — |
| Expiry date | Oct 21, 2033 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB65B31/003
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A non-addictive analgesic sustained-release drug delivery system, comprising: (1) a narcotic analgesic drug having a concentration of 1 mg/ml-160 mg/ml, the drug being selected from a group consisting of: a local analgesic drug, and the combination of the local analgesic drug and a nonsteroidal analgesic drug and/or an opioid analgesic drug; (2) a drug menstruum in a proportion of 1%-75% (v/v), the menstruum being selected from a group consisting of benzyl alcohol, ethanol, benzyl benzoate, ethyl lactate, and tetrahydrofurfuryl polyethylene glycol ether; and (3) a drug sustained-release formulation having a proportion of 25%-99% (v/v), the sustained-release formulation being selected from a group consisting of natural vegetable oil, synthetic lipid, artificially improved half-natural lipid and derivative thereof. Also disclosed are a preparation process and use of the sustained-release drug delivery system.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.