CD229 CAR T cells and methods of use thereof
US11365252B2 · kind B2 · utility
0Cited by
24References
20Claims
0Family size
Assignee
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Key dates
| Filing date | Jul 19, 2017 |
| Grant date | Jun 21, 2022 |
| Priority date | — |
| Expiry date | Mar 22, 2038 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2510/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Disclosed are chimeric antigen receptor (CAR) polypeptides comprising a CD229 antigen binding domain, a transmembrane domain, and an intracellular signaling domain. Disclosed are nucleic acid sequences capable of encoding a CAR polypeptide comprising a CD229 antigen binding domain, a transmembrane domain, and an intracellular signaling domain. Also disclosed are vectors and cells comprising one or both of the CAR polypeptides and nucleic acid sequences capable of encoding CAR polypeptides. Also disclosed are methods of treating.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.