Enhanced immune effector cells and use thereof
US11365394B2 · kind B2 · utility
8Cited by
12References
20Claims
0Family size
Assignee
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Key dates
| Filing date | Feb 19, 2021 |
| Grant date | Jun 21, 2022 |
| Priority date | — |
| Expiry date | Feb 19, 2041 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2800/80
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Provided are methods and compositions for obtaining functionally enhanced derivative effector cells obtained from directed differentiation of genomically engineered iPSCs. The derivative cells provided herein have stable and functional genome editing that delivers improved or enhanced therapeutic effects. Also provided are therapeutic compositions and the used thereof comprising the functionally enhanced derivative effector cells alone, or with antibodies or checkpoint inhibitors in combination therapies.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.