Protein microarray assay imager
US11366061B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Jan 23, 2014 |
| Grant date | Jun 21, 2022 |
| Priority date | — |
| Expiry date | Nov 14, 2035 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2223/421
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
An approach is described that combines distinct properties of a specialized porous nitrocellulose film (PNC) with quantum nanoparticles to create an improved assay and detection sensitivity, permitting the development of a camera-based imaging system for fluorescent detection of macromolecules in microarray format. The two properties of PNC that facilitate the approach are an extraordinarily high binding capacity and a newly observed internal scattering of light. Quantum nanoparticles complement these PNC properties by providing a higher level of emitted light than the fluorescent dyes in common microarray use. Overall, the approach allows for instrument cost savings, reduced imaging time, and the ability to remotely image.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.