Systems and methods for magnetic resonance imaging

US11366189B2 · kind B2 · utility

Assignee

• UIH AMERICA, INC. · US

Inventors

• Hui-Hai Liu · Shanghai, CN
• Qi Liu · Beijing, CN
• Yichen Hu · Shanghai, CN

Key dates

• Filing date: Sep 25, 2020
• Grant date: Jun 21, 2022
• Expiry date: Sep 25, 2040

Classification

• Technology area (CPC G): Physics
• CPC primary: G01R33/5617
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

The present disclosure provides a system for MRI. The system may obtain a plurality of echo signals relating to a subject that are excited by an MRI pulse sequence applied to the subject. The system may perform a quantitative measurement on the subject based on the plurality of echo signals. The MRI pulse sequence may include a CEST module configured to selectively excite exchangeable protons or exchangeable molecules in the subject, an RF excitation pulse applied after the CEST module configured to excite a plurality of gradient echoes, and one or more refocusing pulses applied after the RF excitation pulse. In some embodiments, the quantitative measurement may include determining various quantitative parameters including a T1, a T2, a T2*, an R2 value, an R2* value, an R2′, a B0 field, a pH value, an MWF, and an APT simultaneously.