Stimulated emission depletion super-resolution microscope using quick combination of light beams

US11366300B2 · kind B2 · utility

Assignees

• Suzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences · CN
• SUZHOU GUOKE MEDICAL TECHNOLOGY DEVELOPMENT (GROUP) CO., LTD. · CN

Inventors

• Yuguo Tang · 安丰镇, CN
• Yunhai Zhang · Suzhou, CN
• Tongda Wei · 安丰镇, CN
• Jian Chang · Suzhou, CN
• Haomin Yang · 安丰镇, CN
• Lin Ji · Nanhu, CN

Key dates

• Filing date: Oct 12, 2020
• Grant date: Jun 21, 2022
• Expiry date: Jan 5, 2041

Classification

• Technology area (CPC G): Physics
• CPC primary: G02B21/0076
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

A STED super-resolution microscope capable of quick beam combination is disclosed, which includes a STED imaging unit and a beam combination test unit. The excitation light and the depletion light are accurately combined by the beam combination test unit, so that the imaging light spots of the two light beams passing through the STED imaging unit can accurately coincide with each other, thereby obtaining a better super-resolution imaging effect.