Solid polymorphs of a FLNA-binding compound and its hydrochloride salts
US11370791B2 · kind B2 · utility
1Cited by
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9Claims
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Key dates
| Filing date | Feb 21, 2020 |
| Grant date | Jun 28, 2022 |
| Priority date | — |
| Expiry date | Feb 21, 2040 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07B2200/13
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The preparation and properties of crystalline polymorphs and solvates of 1-benzyl-8-methyl-1,4,8-triazaspiro-[4.5]-decan-2-one free base and of the mono- and dihydrochloride salts and solvates thereof are disclosed, as is an amorphous polymorph of the dihydrochloride. A pharmaceutical composition containing one or more polymorphs and a method of using that composition are also disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.