Substituted pyrazoles as LRRK2 inhibitors
US11370796B2 · kind B2 · utility
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18Claims
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Key dates
| Filing date | Dec 3, 2018 |
| Grant date | Jun 28, 2022 |
| Priority date | — |
| Expiry date | Dec 3, 2038 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D487/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A pyrrolo(pyrazolo)pyrimidine compound of Formula 1, a pharmaceutically acceptable salt, a hydrate, a solvate, a prodrug, and an isomer, and pharmaceutical compositions containing the compound are disclosed. The compound of Formula 1 shows excellent LRRK2 inhibitory activity. Method for manufacturing the compound and uses thereof as an LRRK2 inhibitor and methods for treating or preventing degenerative brain diseases employing the compound are disclosed:
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.