Monoclonal antibody binding to human IL-5, preparation method therefor and use thereof
US11370836B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Nov 30, 2018 |
| Grant date | Jun 28, 2022 |
| Priority date | — |
| Expiry date | Apr 15, 2039 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/53
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Disclosed is a monoclonal antibody that binds to human IL-5. The monoclonal antibody that binds to human IL-5 has a good biological activity for inhibiting TF-1 cell proliferation induced by IL-5 and blocking the interaction between IL-5 and IL-5RA, has a different antigen epitope from the known anti-human IL-5 antibody, can be used for preparing drugs for treating diseases mediated by the over-expression of eosinophilic granulocytes (such as asthma), and has a good clinical application prospect.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.