Articles for diagnosis of liver fibrosis

US11371097B2 · kind B2 · utility

Assignee

• The Government of the United States, as represented by the Secretary of the Army · US

Inventors

• Mohamed Diwan M. Abdulhameed · Frederick, US
• Gregory J. Tawa · Doylestown, US
• Danielle L. Ippolito · Frederick, US
• John A. Lewis · Brooks Road, US
• Sven Anders Wallqvist · Halmstad, SE
• Jonathan D. Stallings · Frederick, US
• Matthew G. Permenter · Knoxville, US

Key dates

• Filing date: Jan 29, 2016
• Grant date: Jun 28, 2022
• Expiry date: Oct 2, 2037

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N2800/56
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

Disclosed are methods and articles (e.g., gene arrays or antibodies) for determining the progression or regression of liver fibrosis, for the diagnosis of liver disease, and for screening compounds for hepatotoxicity and efficacy against liver fibrosis. Related therapeutic methods also are disclosed.