Digital analysis of blood samples to determine efficacy of cancer therapies for specific cancers
US11371101B2 · kind B2 · utility
1Cited by
6References
15Claims
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Key dates
| Filing date | Oct 27, 2017 |
| Grant date | Jun 28, 2022 |
| Priority date | — |
| Expiry date | Nov 10, 2037 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q2600/158
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
This disclosure relates to new assay methods for analysis of RNA, e.g., from circulating tumor cells (CTCs), tumor-specific exosomes, or tumor-specific cell-free RNA, in a subject's blood sample to determine an expression level of one or more lineage markers in the blood sample, wherein the expression level of a specific one or more lineage markers is predictive of progression-free survival and overall survival for a specific anti-cancer treatment regimen in that subject.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.