In vivo optical flow imaging
US11375913B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Jan 12, 2018 |
| Grant date | Jul 5, 2022 |
| Priority date | — |
| Expiry date | Sep 11, 2039 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01B9/02091
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Described herein is an optical coherence tomograph (OCT) angiography technique based on the comparison of OCT signal amplitude to provide flow information. The full OCT spectrum can be split into several narrower spectral bands, resulting in the OCT resolution cell in each band being isotropic and less susceptible to axial motion nose. Inter-B-scan flow values can be determined using the individual spectral bands separately and then averaged. Recombining the flow images from the spectral bands yields angiograms that use the full information in the entire OCT spectral range. Such images provide significant improvement of signal-to-noise ratio (SNR) for both flow detection and connectivity of microvascular networks compared to other techniques. Further, creation of isotropic resolution cells can be useful for quantifying flow having equal sensitivity to axial and transverse flow.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.