Compounds and methods for treating influenza

US11377418B2 · kind B2 · utility

Assignee

• Macau University of Science and Technology · CN

Inventors

• Zhi-Hong Jiang · Taipa, CN
• Nanshan Zhong
• Zifeng Yang
• Jingrong Wang · Qiaonanxiang, CN
• Qitong Feng
• Xiaobo Zhou · Macau, CN
• Beixian Zhou

Key dates

• Filing date: Dec 3, 2020
• Grant date: Jul 5, 2022
• Expiry date: Dec 3, 2040

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07B2200/07
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

A compound including a structure of Formula (I) and a preparation method thereof, wherein R1 is —OH, —CH2OH, or —OCOCH3; R2, R3, and R4 are independently —H, —CH3 or —F, and at least one of R2, R3, and R4 is —F. A method for treating a subject suffering from a viral disease includes administering an effective amount of said compound or a solvate thereof to the subject.