Compounds to inhibit bacterial s-layer protein assembly
US11377484B2 · kind B2 · utility
0Cited by
7References
11Claims
0Family size
Assignees
Inventors
Key dates
| Filing date | Oct 2, 2018 |
| Grant date | Jul 5, 2022 |
| Priority date | — |
| Expiry date | Oct 2, 2038 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2333/32
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention relates to the field of bacterial Surface (S)-layer proteins, in particular to compounds capable of disrupting the bacterial S-Layer, specifically the S-Layer of Bacillus anthracis. More particularly, the invention provides for single domain antibodies for diagnosis and treatment of infection caused by pathogens with an S-Layer, in particular of Bacillus anthracis infection. The invention relates to S-Layer protein binding agents inhibiting bacterial growth and interrupting S-Layer assembly, useful in the treatment of bacterial infection, more specifically treatment of anthrax disease.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.