PD-L1 binding polypeptide or composite
US11377497B2 · kind B2 · utility
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11Claims
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Key dates
| Filing date | Jan 23, 2018 |
| Grant date | Jul 5, 2022 |
| Priority date | — |
| Expiry date | Jan 16, 2039 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2317/76
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention relates to the field of medical biology, and discloses a high-resolution crystal structure of a complex of PD-L1-blocking heavy-chain single-domain antibody KN035 binding with PD-L1, and the use of the crystal structure. The invention also relates to novel PD-L1 binding polypeptides or compounds developed based on the crystal structure and uses thereof.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.