Calibration for multi-component assays
US11378573B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Dec 2, 2015 |
| Grant date | Jul 5, 2022 |
| Priority date | — |
| Expiry date | Mar 30, 2037 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2333/4737
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A method of analyzing a biological sample using an analyzer and an assay. The method comprises providing the assay for producing the signal. The assay has two or more predetermined number of components. Each of the predetermined components has a distinct relation between the intensive property and the signal. The method further comprises providing calibration samples with known values for the intensive property and measuring a calibration signal for each of the calibration samples. The method further comprises determining a calibration by fitting a calibration function to the calibration signal for each of the calibration samples and the known values for the intensive property. The calibration function is equivalent to a constant plus an exponential decay term for each of the predetermined number of components. The method further comprises measuring the signal of the sample using the analyzer and the assay, and calculating the intensive property using the calibration.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.