Dextromethorphan transdermal delivery device
US11382869B2 · kind B2 · utility
Assignee
Inventor
Key dates
| Filing date | Oct 3, 2018 |
| Grant date | Jul 12, 2022 |
| Priority date | — |
| Expiry date | Oct 3, 2038 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K31/49
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Provided herein are transdermal delivery devices comprising dextromethorphan. The transdermal delivery device can be characterized by the novel design, for example, with an adhesive layer and a reservoir layer, with an adhesive layer comprising a mixture of two adhesives, and/or with a skin permeation enhancer, e.g., in an amount that can significantly enhance the flux of dextromethorphan. The transdermal delivery device can also be characterized by its in vitro and/or in vivo release profile, for example, that can provide a desired pharmacokinetic profile described herein. Also provided herein are methods of administering dextromethorphan, and methods of treating a disease or disorder described herein, using the transdermal delivery device herein.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.