Pharmaceutical compositions for use in the treatment of cardiovascular calcification
US11382894B2 · kind B2 · utility
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5Claims
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Key dates
| Filing date | Mar 29, 2018 |
| Grant date | Jul 12, 2022 |
| Priority date | — |
| Expiry date | Dec 6, 2038 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2800/32
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The inventors demonstrate that the phosphatase and hydrolase domains of soluble epoxide hydrolase (sEH) regulate the cardiovascular calcification process and revealed that inhibition of the phosphatase domain of sEH could represent a new pharmacological target in the prevention of cardiovascular calcification. The present invention thus relates to a therapeutically effective amount of an inhibitor of phosphatase activity of soluble epoxide hydrolase for use in a method of treating cardiovascular calcification in a subject in need thereof.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.