Reloadable hydrogel system for treating brain conditions
US11382983B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Jan 12, 2018 |
| Grant date | Jul 12, 2022 |
| Priority date | — |
| Expiry date | Aug 26, 2038 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K9/06
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A drug delivery system and methods of using such for delivering a peglyated therapeutic agent to brain. The drug delivery system may comprise an antibody, which binds polyethylene glycol (PEG), wherein the antibody is embedded in a hydrogel, which may comprises one or more biodegradable polymers, up to 60% of which contain inter-chain or intra-chain covalent crosslinks. The amount of the antibody in the drug delivery system can be about 1-2 μg per μl of the hydrogel.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.