Patent · US Active

Process for preparing esters of N-acylated amino acids with acid-labile keto protective group functions

US11384061B2 · kind B2 · utility

0Cited by

3References

4Claims

0Family size

Assignee

BAYER HEALTHCARE LLC · DE

Inventors

Albert Schnatterer · Leverkusen, DE
Michael Dockner
Peter Bruechner · Krefeld, DE
Thomas Himmler · Odenthal, DE

Key dates

Filing date	Apr 15, 2019
Grant date	Jul 12, 2022
Priority date	—
Expiry date	Apr 15, 2039

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D491/113
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

The present invention relates to a novel process for the esterification of N-acylated amino acids which contain an acid-labile keto protective group under alkaline conditions without using a polar aprotic solvent, in which the N-acylated amino acid with acid-labile keto protective group prepared in situ is esterified using an alkyl halide or a mono- or dialkyl ester of sulfuric acid.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.